Bacillus subtilis: Mechanisms of Action

11-01-2025


Bacillus subtilis


Below, the primary mechanisms of Bacillus subtilis will be detailed.


1. The active substances produced during the growth of the Bacillus subtilis bacteria, such as subtilisin, polymyxin, nystatin, and gramicidin have a significant inhibitory effect on pathogenic bacteria or conditional pathogens of endogenous infection.

2. Bacillus subtilis rapidly consumes free oxygen in the intestine, causing intestinal hypoxia, promoting the growth of beneficial anaerobic bacteria, and indirectly inhibiting the growth of other pathogenic bacteria.

3. Bacillus subtilisstimulates the growth and development of animal (human) immune organs, activate T and B lymphocytes, increase the levels of immunoglobulins and antibodies, enhance cellular immunity and humoral immunity, and improve group immunity.

4. Bacillus subtilis bacteria synthesize enzymes such as α-amylase, protease, lipase, cellulase, etc., which work together with digestive enzymes in the animal (human) body in the digestive tract.

5. Bacillus subtilis can also synthesize a variety of B vitamins such as vitamin B1, B2, B6, niacin, etc., and increase the activity of interferon and macrophages in the animal (human) body.

6. Bacillus subtilis promotes spore formation and micro-encapsulation of special bacteria. It has good stability in the spore state and is resistant to oxidation; it is resistant to extrusion; it is resistant to high temperatures, can withstand high temperatures of 60°C for a long time, and can survive for 20 minutes at 120°C; it is resistant to acid and alkali, can maintain activity in the acidic stomach environment, can withstand the attack of saliva and bile, and is a live bacteria among microorganisms that can 100% directly reach the large and small intestines.

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